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Welcome to the Team Justina!

A warm welcome to Justina Heslop who joins us to support the group with reporting, events, social media and engagement. Justina has worked as a Research Project Manager at Newcastle University since 2017, supporting several research groups and projects across Chemistry and Engineering most notable the North East Centre for Energy Materials.

Welcome to our new PhD Students

A warm welcome to our new PhD students who joined us on 1st October 2021. Emma Wadforth, Oliwia Rebacz, Tom Smith, and Tim Bell will be working across a number of exciting projects funded by BBSRC, EPSRC MoS Med CTD, ERC.

Congratulations Benoit!

Many congratulations to Dr Benoit Darlot on successfully defending his DPhil thesis on Design of modulatory peptides against chemokines. Benoit was an EPSRC Synthesis for Biology and Medicine CDT student, Oxford and was co-supervised by co-supervised by Prof Shoumo Bhattacharya (Radcliffe Department of Medicine, Oxford).  He was awarded an EPSRC Doctoral Prize and continued as a postdoc in the lab for six months. As well as his sterling work on tick protein derived anti-inflammatory peptides, Benoit was an active member of the research community.  He was a member of the NU Rainbow Network steering committee and the committee for the NuTEC RSC local section where he  endeavoured to support his… Read More »Congratulations Benoit!

Welcome to the Team Marie-Helene!

Welcome to our new research associate Marie-Helene Ruchaud who joins us from Newcastle University Medical School where she worked on a variety of projects involving innate immunology and inflammation. These included studying the human immune response in epithelial cells following Enteropathogenic E.Coli (EPEC) infection along with the regulation of the innate immune response in severe lung injury & infection or testing potential antimicrobial agents such as p97 inhibitors acting as DNaA inhibitors in Staphyloccocus aureus and Pseudomonas aeruginosa. She is currently developing quantitative cellular assays to investigate inhibition of SARS-Cov2 main protease by cyclic peptides. A warm welcome to the team!

Joanna’s viva and baby!

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A double congratulations is owed to our own Dr Joanna Bonnici, who successfully navigated the perils of a pandemic-Zoom viva to defend her DPhil thesis in December. With hardly a breath to spare she started a family with her husband Tom, as baby Elsie arrived in late January this year. Joanna has been an asset to the lab throughout her DPhil and is almost certainly, definitely, looking forward to more happy years of research to come… Many congratulations to them all and we look forward to using both events as an excuse to over-celebrate later this year once we are all vaccinated!

Editing a Special Issue on Chemical Genetics and Epigenetics

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We’re delighted to publish a special issue with Ganesan in Current Opinion in Chemical Biology around Chemical Genetics and Epigenetics, with contributions from some world leading scientists and long-time collaborators. We’re excited by their contributions and hope you enjoy finding something useful and interesting. Contributors include Sir Prof. Shankar Balasubramanian, Manfred Jung, Udo Oppermann, Maria Berdasco, Antonello Mai, Marianne Rots, Gianluca Sbardella, Alessio Ciulli, Danica Fujimori, Chris Schofield, Angel de Lera and many others. Click here to read!

Congratulations Kieran

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Many congratulations to Kieran Thow for completing his Part II. Kieran made significant progress on the biochemical characterisations of TET-related enzyme. All the best for the future!

Newcastle University Rainbow Network steering committee member

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Benoit Darlot is now an active member of the NU Rainbow Network steering committee. He is investing his time and efforts to defend LGBTQ+ rights on the campus and to foster institutional change within the university to tackle EDI issues. (Blog by B.D.)

Paper in Epigenetics

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Paper in Epigenetics: Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications – Collaborative work with Chris Schofield, Louise Walport, James McCullagh, Richard Hopkinson and Emily Flashman groups where we report the use of LCMS based intact histone assay to look at the global changes in histone PTMs in response to hypoxia / compound treatment – read the full paper here  

Back to work

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Having a socially distanced out-door lunch break at Newcastle University. Great to see the team come together again! Hopefully all the group members will be able to return to work soon, both at Newcastle and Oxford.