A warm welcome to Harriet Stanway-Gordon who started in the group this month. Harriet undertook her PhD with Prof. Mike Waring in the Medicinal Chemistry group at Newcastle, focusing on the development of micellar-mediated DNA-compatible chemistry for use in DNA-encoded library (DEL) synthesis, where she was involved in the development and optimisation of multiple classes of reactions. Through the application of this methodology, a proposed new class of drug molecules, termed cyclic peptide small molecule hybrids (CyPeMs) can now be constructed within DELs. Harriet has been awarded an EPSRC doctoral prize to expand upon her PhD research, involving the synthesis of CyPeM DELs and subsequent selection against several challenging epigenetic… Read More »Welcome to the group Harriet!
Many congratulations to group member Grace Roper and her husband Cameron Taylor (a medicinal chemist!) on their wedding! Thanks for inviting us to share your day. We wish these two wonderfully talented scientists all the best!
Some great talks and networking at the Royal Society of Chemistry Interest Group for Chemical Biology and Bioorganic Chemistry postgraduate meeting at York University on 4th April. Great to be back to in-person conferences! It was a great opportunity for our early career researchers to share their latest research with colleagues from across a broad range of chemical biology backgrounds.
On Tuesday 15th March we hosted a Chemical biology workshop at Newcastle University, involving academics across the faculty of medicine science and the school of natural and environment science. Ten academics delivered flash presentations on diverse areas of research (see below). A great way to get the group talking and learning about the chemical biology research going on across the university. Engineered protein polymers for high performance, multi-functional biomaterials Daniel Peters and David A Fulton Structure guided drug discovery for loss-of-function diseases Wyatt Yue (Cyclic) peptide discovery platform Akane Kawamura In vivo Non-invasive Small Animal Molecular Imaging Services Saimir Luli Mass spectrometry tools in drug discovery Matthias Trost Biocatalysts… Read More »Chemical Biology Workshop
This week the Kawamura group was thrilled to host Dr Martin Münzel, scientific director in research chemistry at Novo Nordisk. Martin is a long-time collaborator with the group and gave a fascinating talk on the use of mRNA display in drug discovery workflows as well as engaging in some stimulating conversations about peptide chemistry. Martin is also a MosMed CDT industrial supervisor to group member Tom Smith. We’d love to have you back anytime, Martin!
2021 has continued to be challenging for all of us, however the group has continued to progress and we have much to celebrate. The much anticipated Kawamura group Winter Symposium took place at last on 16th Feb 2022. We reflected on two years since the group celebrated official handover of the Chemical biology labs (Feb 2020). In this time we have more than doubled the footprint of the group, forged ahead with equipment purchases and set-up the synthesis/cold room space. Thanks to all the hard work of the group! At the symposium we had a fantastic overview from the team showcasing all the diverse and exciting research happening across the… Read More »Kawamura Group 2021 Highlights
A warm welcome to our new Mchem Students, Oliver Crosby, Valeria Cobiltean and Hannah Hamilton who joined the group in January 2022. We hope to give them a rich experience learning from the diverse and fascinating science happening in the group and getting involved in our outreach activities.
We are recruiting! If you are interested in joining a vibrant, friendly and inclusive chemical biology team and work in a brand new chemical biology lab in the heart of Newcastle city centre, please apply here. We are looking to appoint two highly motivated and ambitious Research Assistants/Associates in Chemical Biology. We would like you to be suitably qualified with knowledge of: – Organic Chemistry / Chemical biology – Cell biology This is an exciting opportunity to contribute to the Cancer Research UK programme funded work on histone demethylases (KDMs), a class of enzymes involved in epigenetic signalling. Dysregulation of some KDMs is strongly linked to cancer and some are… Read More »We are recruiting!
Earlier this month, Tom McAllister left his role as senior research associate in the group to start his prestigious five-year Royal Society University Research Fellowship. He will develop new ways to understand how proteins and carbohydrates interact. Projects include determining how human glycosylating enzymes implicated in cancer recognise their protein targets, furthering our fundamental understanding and paving the way for new diagnostics or treatments. Another is developing a novel alternative mode of treatment for the wheat pathogen, Z. tritici the causative agent of septoria leaf blotch disease. Z. tritici causes losses of ~20% crop yield and current fungicidal treatment costs €1B/year in Europe alone – this research will allow the… Read More »Tom starts his Royal Society University Research Fellowship
A warm welcome to Justina Heslop who joins us to support the group with reporting, events, social media and engagement. Justina has worked as a Research Project Manager at Newcastle University since 2017, supporting several research groups and projects across Chemistry and Engineering most notable the North East Centre for Energy Materials.