In June 2023, Joanna Bonnici and Harriet Stanway-Gordon – two of our Post Doctoral Research Associates – returned to work after maternity leave. The team is excited to have them back, and looking forward to plenty of baby photos and supporting them in balancing work and home life as parents. Joanna: “I’m excited to return to work to face new challenges that don’t involve changing nappies or deciphering the meaning behind my baby’s cries.” Harriet: “Can’t believe I’m heading back to work already – feels like only yesterday Ziggy arrived! Looking forward to getting back to some semblance of normality (although I am going to miss spending most of… Read More »Joanna & Harriet Return from Maternity Leave
On 16th and 17th May, it was once again time for the Molecular Sciences for Medicine (MoSMed) CDT annual conference. The Newcastle and Durham University students descended on St James’ Park for these two days; each year, this is a great opportunity to catch up with the rest of the cohort from both universities as well as learn about the innovative science going on in the programme. Our second year PhD students Emma and Tom presented posters showcasing their research, whilst third year PhD student Siddique gave a presentation followed by a Q&A session. The conference was also an opportunity for our early career researchers to network with industry partners,… Read More »MoSMed Conference 2023
After months of hard work Maddy Sayers and Maia Evans have successfully completed their MChem thesis and viva in the Kawamura Group. Their work has involved investigating different roles and uses for cyclic peptides as chemical probes working with PhD students Siddique and Emma. Congratulations and well done on all your hard work, it has been a joy to work with you! We are looking forward to seeing where you go next.
On Monday 13 February Grace defended her DPhil thesis. She wrote a blog all about the challenges and celebrations of her PhD journey. I began my PhD in Oxford as an Oxford-GSK-Crick Chemical Biology CDT student, with 9 months training in chemical biology through taught courses and two 12-week lab placements. The lab placements were particularly helpful for broadening my skill set, allowing me to try two completely different projects. For one project I spent time at GSK working on photoreactive cyclic peptide probes, and for the other I was studying the effect of tissue stiffness on (myo)fibroblast biology using immortal and primary cell lines. I chose to work in… Read More »Grace successfully defends her DPhil thesis!
Written by: Tom Smith. From October to December 2022, I had the privilege of visiting the R&D site of Novo Nordisk in Denmark as part of the Kawamura Group’s ongoing collaboration with this pharmaceutical company. It was incredible to experience the cutting-edge science going on there; the company specialises in treating diabetes as well as a variety of other chronic illnesses, and the wealth of expertise they have onsite in peptide chemistry and many other areas was fantastic to be part of. During my placement I was able to undertake various projects including massively parallel peptide synthesis, high throughput screening assays, and DNA library sequencing analysis. As well as improving… Read More »Tom Visits Novo Nordisk in Denmark
A very warm welcome to Chris Mullins, who joins the group as a PhD student as part of the Molecular Sciences for Medicine (MoSMed) CDT. Chris comes to us from Evox Therapeutics, Oxford where he specialised in the downstream purification of exosomes for rare disease indications. He graduated from The University of Warwick with an MBio in Biochemistry with Industrial Placement, during which he spent 12-months at UCB in Slough developing novel engineered antibody formats. Welcome to the group Chris!
We are excited to welcome Dr. Rob Dawber to group as a Postdoctoral Research Associate. Rob received his MChem degree at the University of Leeds in 2018. In July 2022, Rob completed his PhD at the same institute through the MRC DiMeN DTP programme, where he developed peptidomimetic inhibitors of key protein-protein interactions of the Aurora A kinase under the supervision of Prof. Richard Bayliss and Prof. Andy Wilson. Rob will be investigating lysine demethylases (KDMs) in relation to the chemistry of epigenetics and associated cancers. Welcome Rob!
On Friday 1st July 2022 we hosted the second Chemical biology workshop at Newcastle University Groups from across the faculty of medicine science and the school of natural and environment science presented a quick synopsis of their research with the aim to spark ideas for collaboration and more awareness of the diverse Chem Bio research happening at Newcastle University. Ten academics delivered flash presentations on diverse areas of research (see below). The talks were followed by a poster session where our early career researchers showcased their work and networked with colleagues from across the university. Exploring mechanisms of kinase inhibitor resistance in MYC driven lymphoma, Neil Perkins, FMS Understanding protein… Read More »Summer Newcastle University Chemical Biology Workshop
A warm welcome to Harriet Stanway-Gordon who started in the group this month. Harriet undertook her PhD with Prof. Mike Waring in the Medicinal Chemistry group at Newcastle, focusing on the development of micellar-mediated DNA-compatible chemistry for use in DNA-encoded library (DEL) synthesis, where she was involved in the development and optimisation of multiple classes of reactions. Through the application of this methodology, a proposed new class of drug molecules, termed cyclic peptide small molecule hybrids (CyPeMs) can now be constructed within DELs. Harriet has been awarded an EPSRC doctoral prize to expand upon her PhD research, involving the synthesis of CyPeM DELs and subsequent selection against several challenging epigenetic… Read More »Welcome to the group Harriet!