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Paper in Oncogene

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Paper in Oncogene – Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancer. Our collaborative work with Dr Nathan Lack’s laboratory (Koç University / Turkey and Vancouver Prostate Centre /Canada) is finally out! Hilal Saraç has led this study on how KDM3B has been identified to be important in the proliferation of castrate resistant prostate cancers. This work was funded by the Royal Society Newton Advance Fellowship. Hilal’s beautiful waterfall plot figure – epigenetic shRNA library screening identifies KDM3B (red) to be essential for CRPC proliferation 

Dr Roman Belle

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Many Congratulations to Roman Belle for successfully defending his DPhil thesis titled “Histone Lysine and DNA Methylation: Dynamic Marks in the Chromatin”! Thanks to Dr Paola Arimondo from Institute Pasteur and James McCullagh for being his examiners.

Epigenetics exhibit at the Oxford Science + Ideas Festival

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We had a fantastic day engaging with members of the public and talking about Epigenetics at the Oxford Science + Ideas festival. Children enjoyed modifying our plasticine histone model, and everyone appreciated real world examples of how Epigenetics is an important area of research. We showed people that identical twins differ because of the different environments they experience, using NASA twins Scott and Mark Kelly as a unique example of two very different environments! We also found some great examples of how Epigenetics affects animals: bees have completely different roles based on their diet during development, and that the sex of some species of turtles differ depending on the temperature… Read More »Epigenetics exhibit at the Oxford Science + Ideas Festival

2019 RSC CBBG Postgraduate Symposium, Southampton

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Kawamura Group DPhil students presented their work at the RSC Chemical Biology and Bio–organic Group Postgraduate Symposium in Southampton. Great job Loane Serano, Klem Simelis, Grace Roper & Raphael Reinbold for presenting their posters, and Benoit Darlot for the oral presentation on his exciting work on anti-inflammatory peptides derived from tick saliva proteins – our collaborative work with Prof. Shoumo Bhattacharya.

Dr Yara Alenazi

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Congratulations Yara Alenazi for completing her D.Phil, thesis title “Targeting the chemokine signalling pathway using tick saliva peptides”. Thank you to the examiners Prof. Antje Beling and Prof. Charles Redwood. (Joint supervision – Prof. Shoumo Bhattacharya)

Dr James Eaton

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Many congratulations to James Eaton for successfully defending his D.Phil thesis on “Characterisation of Novel Evasins”. Thanks to Prof. Gerard Graham from University of Glasgow and Prof. Chris Schofield for being his examiner, and BHF CRE for supporting his studentship. Read James’ work on tick saliva evasins [Ref 55][Ref 67][Ref 69] (Joint-supervision Prof. Shoumo Bhattacharya)