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Book Chapter – Chemical Epigenetics edited by Antonello Mai

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Delighted to contribute two chapters in Chemical Epigenetics in Topics in Medicinal Chemistry book series edited by Prof. Antonello Mai. Our review on “Inhibitors of JmjC-containing Histone Demethylases” by Miranda Wright, together with Prof. Paul Brennan (Target Discovery Institute, Oxford), focuses on the recent advances in JmjC-KDM inhibitor development from a structural perspective. In “Chemical Compounds Targeting DNA Methylation and Hydroxymethylation” by Roman Bell, together with Dr Paola Arimondo (Institut Pasteur, Paris), we review the recent developments in DNMT and TET inhibitors.